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保定地区猪附红细胞体病流行病学调查与防治研究

标题: 保定地区猪附红细胞体病流行病学调查与防治研究
英文标题: Investigation of the epidemic situation Of eperythrozoon suis in baoding area
作者: 高婕
出版时间: 2011-01-01
所在大学: 河北农业大学
关键词: 猪,附红细胞体,流行病学,防治
英文关键词: Swine,Eperythrozoon suis,epidemiology,prevention and treatment
论文级别: 硕士
学位: 学位论文
导师: 秦建华%逯纪成
专业: 预防兽医学
提交时间: 2011
摘要: 近几年来,猪附红细胞体病在保定市多个地区的猪场都有发生,猪感染附红细胞体后,会导致生产能力下降,甚至危及猪的生命,对养猪生产造成了重大经济损失.本试验研究立足于保定市养猪业实际,研究的目的是要明确保定市猪附红细胞体病的流行情况,筛选出治疗猪附红细胞体病的有效药物和方法,制定出猪附红细胞体病的综合预防措施,研究的意义在于通过采取有效的防治措施,减少猪附红细胞体病发生,为保定市养猪企业服务.本试验采用动物疫病流行病学调查和实验室检测方法,对保定市6个县,30个不同规模的猪场和20个散养户,随机抽取2040份猪血样,进行猪附红细胞体的流行病学调查.结果显示:保定市各县猪附红细胞体的感染率均达到64%以上,总样本阳性感染率为74.25%,表明猪附红细胞体的感染在保定市猪群中广泛存在.不同日龄的猪均有感染,断奶仔猪感染率高达82.9%;猪附红细胞体存在垂直传播;一年四季均有感染,尤其是夏季蚊虫较多的季节,猪群中附红细胞体感染较严重,高达86.67%.应给与高度重视.对自然感染附红细胞体病的病猪进行分组治疗试验,在饲养管理水平一致的条件下,分别选取复方制剂血虫混感净、中药方剂圆蓝附红清、单方广谱抗菌药物长效土霉素进行注射用药,结果显示:所选药物显示出不同的疗效.血虫混感净杀灭本病原同时防治其他细菌混合感染,效果最明显; 圆蓝附红清中药组合有协同作用,有明显治疗效果;二者治疗效果均高于长效土霉素.所以联合用药治疗效果优于单方用药.同时结合维康质对机体扶正治疗,提高猪机体抗病能力,疗效最佳. 选择自然感染附红细胞体阳性的断奶仔猪和临产母猪,分别用复方合成药物附红舒、单方广谱抗菌药物强力霉素、提高机体免疫药物易宁益拌饲进行药物预防试验,结果显示:所选药物均显示出一定的效果,从猪群的发病率和仔猪生长情况比较,附红舒和易宁益组好于强力霉素组.临床观察,对感染猪群在应激阶段进行药物预防,提高猪机体自身免疫水平,可有效的预防猪附红细胞体病的发生.??
英文摘要: In recent years, Eperythrozoon suis was found in pig farms around Baoding district. When the pigs were infected by Eperythrozoon, the lighter ones caused productivity decreased, the severe ones could cause the pigs to die, which caused giant loss to swine industry. In this experiment, we focused on swine industry practice of Baoding district, to investigate epidemiological characters of Eperythrozoon suis in Baoding district, look for active drugs and methods on treatment of Eperythrozoon suis, find the integrate control methods about this disease, protect the development of swine industry practice in Baoding district. In this experiment, the traditional animal epidemiological survey and laboratory detection methods were used. The blood samples in 30 swine farms, 20 households around Baoding district were collected and 2040 samples were selected randomly for epidemiological survey of Eperythrozoon suis. The results showed that the infection rate of Eperythrozoon suis was up to 64%, the total positive samples infection rate was 74.25%. These indicated that infection of E.suis in Baoding district were popular. At the same time, the study also showed that the different age of swines were infected by E.suis, and the infection rates of weaned piglets were up to 82.9%. This disease was transmitted vertically. The infection happened all over the years, especially in the summer mosquito season, the infection rates were up to 86.67%. For the nature infection E.suis proceed divide into groups cure experiment .IN the same condition ,we choose Doxycycline, traditional Chinese medicine prescription Yuanlanfuhongqing had therapeutic effects on E.suis. The drug treatment for E.suis showed: Xuechonghunganjing was compound prescription, its main components Deoxycycline, Sulfamonomethoxine Sodium, baytril were broad spectrum antibiotics, which could prevent and treat combined infection of bacteria. Chinese medicine prescription Yuanlanfuhongqing was herbal drugs mixture, which had synergistic effect. The effect of the compound prescription was better than that of Doxycycline. Therefore the drug combination was better than simple recipe. Meanwhile, united with weikangzhi to increase the immunty for the disease resistance was important. Using compound drug fuhongshu, simple broad spectrum antibiotic Doxycycline and immunopotentiator yiningyi respectively to weaned pig and parturient pig, the result of the preventing experiment is that the drugs which were chosed took effect. Fuhongshu is better than yiningyi. When the drugs were used in stress period, which could prevent the devel opment of Eperythrozoon suis effectively. Therefore the prevention of Eperythrozoon suis should promote autoimmunity level, so as to protect swinery health.??