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中药"孕宝"对子宫炎病牛肿瘤坏死因子-α含量的影响

标题: 中药"孕宝"对子宫炎病牛肿瘤坏死因子-α含量的影响
英文标题: EFFECTS OF THE CHINESE HERBAL PRESCRIPTION YUN BAO ON UTERINE TUMOR NECROSIS FACTOR-ALPHA CONTENTS OF DAIRY COWS WITH ENDOMETRITIS
作者: 李呈敏,钟秀会,邓泽沛,周占祥,刘翠艳
英文作者: LI CHENGMIN,ZHONG XIUHUI,DENG ZEPEI,ZHOU ZHANXIANG,LIU CUIYAN
出版时间: 2001-01-01
机构: 河北农业大学
关键词: 母牛,子宫炎,肿瘤坏死因子-α,ELISA,中药
刊名: 畜牧兽医学报
英文刊名: ACTA VETERINARIA ET ZOOTECHNICA SINICA
ISSN: 0366-6964
卷号: 002
基金: ^A国家自然科学基金^B39770543^D1%^A北京市自然科学基金^B6982014^D2%^A河北省自然科学基金^B399131^D3
页码: 146-151
分类号: S853.51
摘要: 为了探讨中药"孕宝"治疗母牛子宫炎提高受胎率的作用机理,本试验用ELISA方法测定了病牛服用中药前后血清及子宫粘液中肿瘤坏死因子-α(TNF-α)的含量(用OD值表示).结果患子宫炎病牛子宫粘液和血清中OD值均高于健康牛.服用中药使病牛子宫粘液的OD值由0.2358±0.2821下降至0.0653±0.0267(N=8),对照组病牛由0.2802±0.2772上升至0.3602±0.2763(N=6).用药组病牛血清OD值由0.6885±0.1838降至0.5328±0.1058(N=8),而对照组无明显变化(N=6).这些试验表明,中药孕宝有降低子宫炎病牛炎性细胞因子TNF-α的作用.
英文摘要: In order to investigate the relevant mechanisms of the Chinese herbal prescription YUNBAO in treatment of endometritis in dairy cows,tumor necrosis factor-α(TNF-α) contents in uterine mucus and serum were assayed by ELISA (expressed in OD values).Both the uterine and serum TNF-α contents were higher in the suffering cows than those in the clinical healthy cows.The Chinese herbal treatment brought about the uterine TNF-α OD valus in diseased cows from 0.2358±0.2821 to 0.0653±0.0267(n=8),while the control group showed a little increase (from 0.2802±0.2772 to 0.3602±0.2763,n=6) in OD values,In serum,the OD values were downregulated,from 0.6885±0.1838 to 0.5328±0.1058(n=8)in the treatment group,but no change was found in the control group(n=6).These results indicate that the Chinese herbal prescription conld be able to downregulate the inflammatory cytokine TNF-α in endometritis cows.